Chief Investigator Prof. Abhishek AbhishekProfessor of Rheumatology,Faculty of Medicine & Health SciencesUniversity of Nottingham Investigators Prof. Danny AltmannProfessor of ImmunologyImperial College London Dr James BluettSenior Clinical Lecturer &Honorary Consultant RheumatologistUniversity of ManchesterProf. Rosemary BoytonProfessor of Immunology &Respiratory Medicine and Joint Lead ApplicantImperial College London Dr Laura CoatesNIHR Clinical Scientist &Senior Clinical Research FellowUniversty of OxfordProf. Jonathan CookAssociate ProfessorUniversity of OxfordMs Yvonne Hurt PPI Member Prof. Áine McKnightProfessor of Viral PathologyQueen Mary, University of LondonProf. Jonathan Nguyen-Van-TamProfessor of Health ProtectionUniversity of NottingamInes RombachSenior Medical StatisticianUniversity of SheffieldProf. Ana ValdesProfessor of Molecular &Genetic EpidemiologyUniversity of NottinghamProf. Hywel WilliamsProfessor of DermatoepidemiologyUniversity of Nottingham Trial StatisticiansProf. Jonathan CookAssociate ProfessorUniversity of OxfordNicholas PeckhamMedical StatisticianUniversity of OxfordInes RombachSenior Medical StatisticianUniversity of Sheffield Trial Management TeamJennifer WilliamsClinical Trial ManagerUniversity of OxfordAnne FrancisClinical Trial Operational LeadUniversity of Oxford